Striking the Right Balance in Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis
AAV are a type of small-vessel necrotising vasculitis that manifest as systemic diseases, with pulmonary; ear, nose, and throat; and renal involvement. The key pathological feature of AAV is the presence of ANCA, which can target two neutrophil antigens, myeloperoxidase (MPO) and proteinase 3 (PR3).