Articles

Histotripsy is a non-invasive, non-thermal, and non-ionising focused ultrasound (US) treatment method that destroys tissue through mechanical disruption caused by cavitation. Short-duration (<20 μs) high-pressure US pulses cause the rapid expansion and collapse of endogenous gas bubbles in targeted tissue.

Juan Gómez Rivas | Urology Consultant, Hospital Clinico San Carlos, Madrid, Spain; Assistant Professor, Universidad Complutense de Madrid, Spain

Andrew R.J. Mitchell | Consultant Cardiologist at Jersey General Hospital, Saint Helier, Jersey; Honorary Consultant Cardiologist at Oxford University Hospitals NHS Foundation Trust, UK

Timothy Clinton – Urologic Oncologist and Associate Surgeon, Dana–Farber Cancer Institute and Brigham and Women’s Hospitals, Boston, Massachusetts, USA; Faculty Member, Harvard University, Boston, USA.

David Stukus – Professor of Clinical Pediatrics, Division of Allergy and Immunology; Director, Food Allergy Treatment Center, Nationwide Children’s Hospital and The Ohio State University College of Medicine, Columbus, Ohio, USA

Director of the Center for Complex Coronary Interventions, Minneapolis Heart Institute, Minnesota, USA…

Severe asthma (SA), chronic rhinosinusitis with nasal polyps (CRSwNP), and eosinophilic granulomatosis with polyangiitis (EGPA) are three conditions driven by IL-5 and eosinophilic inflammation. As these conditions have high use of healthcare services, as well as lifestyle and psychological burdens, well-tolerated treatment to achieve optimal control is key.

Setting the scene, Bakris defined CKD as a reduction in kidney function (estimated glomerular filtration rate [eGFR] <60 mL/min/1.73 m2), alongside the presence of albuminuria (≥30 mg/day) as an indication of kidney damage.