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Reproductive Health
2 Mins
8 Aug 2019

Single Nucleotide Variations of Mitotic Arrest Deficient 1 Like 1 (MAD1L1) and MAD2L1 Genes in Products of Conception with Aneuploidy

Miscarriage is a pregnancy loss before the 20th week of the gestation. At least 15% of the recognised pregnancies will be terminated by spontaneous…
Reproductive Health
2 Mins
8 Aug 2019

BESST, a Non-Invasive Computational Tool for Embryo Selection Using Mass Spectral Profiling of Embryo Culture Media

The current gold standard of embryo evaluation is based on morphology and morphokinetics, however there have been many efforts to design non-invasive…
Reproductive Health
1 Mins
8 Aug 2019

To Analyse the Incidence of Ectopic Pregnancy in Fresh Embryo Transfer Compared with Frozen-Thawed Embryo Cycles in a Tertiary Infertility Centre in India

In vitro fertilisation (IVF) is one of the major risk factors for an ectopic pregnancy (EP). Rates of EP in women undergoing IVF range from 2–5%…
Hematology
1 Mins
1 Aug 2019

Tagraxofusp is a Novel Targeted Therapy Directed to CD123

Blastic plasmocytoid dendritic cell neoplasm (BPDCN), a rare, highly aggressive haematologic malignancy, often with cutaneous and other extramedullary…
Hematology
1 Mins
1 Aug 2019

Post-Transplant Cyclophosphamide in HLA Matched and Haploidentical Transplant Recipients Receiving Myeloablative Timed Sequential Busulfan Conditioning Regimen: Results of a Phase II Study

The authors report a prospective Phase II trial to assess (a) if post-transplant cyclophosphamide (PTCy) could be safely incorporated in a timed…
Hematology
1 Mins
1 Aug 2019

Autologous Dendritic Cell Vaccination to Prevent Progression and Relapse in Multiple Myeloma

Data from the National Cancer Institute showed that 50% of myeloma patients survive past 5 years post-diagnosis. This is encouraging but also warns…
Hematology
2 Mins
1 Aug 2019

Gilteritinib Plus Azacitidine in Newly Diagnosed FLT3 Mutated (FLT3mut+) Acute Myeloid Leukaemia Patients Ineligible for Intensive Induction Chemotherapy: Preliminary Findings from the Safety Cohort

Search of more effective treatment for patients with acute myeloid leukaemia (AML) who are ineligible for intensive chemotherapy remains challenging…
Nephrology
2 Mins
30 Jul 2019

Renal Involvement in Eosinophilic Granulomatosis with Polyangiitis

Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotising vasculitis affecting small to medium sized vessels, characteristically…