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7 May 2015

Subclinical Hypothyroidism and its Impact on Reproductive Health

Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) levels in the presence of normal thyroxine (T4) levels.
7 May 2015

Re: State-Of-The-Art Treatment in Castration-Resistant Prostate Cancer – Forward to the past – Again

Castration-resistant prostate cancer (CRPC) management is enjoying a renaissance following the marginal but significant beneficial impact of recent novel…
17 Mar 2015

Editor’s Pick: Paradigm Shift in the Management of Gynaecological Cancers

In this review we highlight novel aspects of diagnostic imaging in gynaecological cancers, the paradigm shift in the surgical management of certain…
17 Mar 2015

Field Cancerisation of the Upper Aerodigestive Tract: Screening for Second Primary Cancers of the Oesophagus in Cancer Survivors

Tobacco, alcohol, and betel quid are the main causes of squamous cell cancers of the upper aerodigestive tract. These substances can cause multifocal…
17 Mar 2015

Perspectives in Surgery of Oligometastatic Non-Small-Cell Lung Cancer

20-50% of patients with newly diagnosed non-small-cell lung cancer (NSCLC) have synchronous metastases. This dramatically affects survival and…
17 Mar 2015

Symptoms and Quality of Life in Gastroenteropancreatic Neuroendocrine Tumours

Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) have the ability to induce symptoms either by their direct mass effect on local tissues…
17 Mar 2015

Recent Advances in Definitive Radiotherapy for Prostate Cancer

Definitive radiation therapy is a well-recognised curative treatment option for localised prostate cancer. A suitable technique, dose, target volume…
17 Mar 2015

Development of Drugs Targeting the PI3K Signalling Pathway in Leukaemias and Lymphomas

The phosphoinositide 3-kinase (PI3K) family of signalling enzymes play a key role in the transduction of signals from activated cell surface receptors…