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9 Mins
12 Nov 2019

Inflection Point: Novel Treatment Options are Forcing Next-Generation Sequencing into Standard of Care for Molecular Profiling in Oncology

With a sustained number of new drugs or combination drugs entering standard of care this year, molecular testing should be…
9 Mins
12 Nov 2019

The Anticancer Power of the Immune System – New Perspectives for Patients with Triple-Negative Breast Cancer

Despite the impressive advances that have been made in cancer diagnosis and therapy, there still exist groups of patients who are not responding to standard anticancer treatments…
3 Mins
12 Nov 2019

Epithelial Myoepithelial Carcinoma of the Hard Palate: A Case Report with a Review of the Literature

Epithelial myoepithelial carcinoma (EMC) was initially described by Donath et al…
8 Mins
12 Nov 2019

PARP Inhibitors as a Novel Treatment Strategy for Patients with BRCA-Mutated Metastatic Breast Cancer

Physiologically, cells are equipped with DNA damage repair systems that can correct various errors…
3 Mins
12 Nov 2019

Branchial Cleft Cyst – A Misdiagnosed Developmental Anomaly

The branchial cleft’s embryological journey begins between the first 3–8 weeks of intrauterine life. Five mesodermal arches form by the inpouching…
9 Mins
12 Nov 2019

Discovery of a ‘Grail-Shaped’ Drug: Ne-ratinib and the Downregulation of Mutant RAS

The drug neratinib (HKI-272, Nerlynx®) was originally developed by Wyeth Research Laboratories, with its initial characterisation published in 2004…
11 Mins
12 Nov 2019

Optimised Tumour Sampling and Processing by a Multidisciplinary Approach for an Accurate Diagnosis in Non-Small Cell Lung Cancer

In the era of target and immunotherapy, the multidisciplinary approach of lung cancer is now mandatory. Close collaboration between pulmonologists…
7 Mins
12 Nov 2019

Follow-Up of Accessory Breast Cancer Patient: Case Report

Accessory breast is a congenital atavism condition. Accessory breast tissue may arise anywhere along the mammary line because of the failure of complete…