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Balancing Exercise and Contraction-induced Muscle Injury in Muscular Dystrophies
9
Mins
June 2024
The rare diseases Duchenne and Becker are X-linked recessive neuromuscular disorders.1 They are characterised by progressive…
Read more
10
Mins
8th December 2022
Editor's Pick: The Pathophysiological Relationship Between Migraine and SARS-CoV-2 Infection: A Comprehensive Literature Review
People with migraine, and individuals with other neurological conditions, have suffered in multiple aspects during the COVID-19 pandemic. This paper will discuss the factors that impacted the neurology department.
13
Mins
8th December 2022
Mexiletine in the Treatment of Non-dystrophic Myotonia: Interviews with Six Medical Experts
NDM includes a group of rare hereditary neuromuscular disorders caused by mutations in the genes that encode sodium or chloride muscle channels.1 Myotonia is the hallmark symptom of NDM and presents as muscle stiffness, often associated with pain, fatigue, and weakness, which can limit function.
9
Mins
8th December 2022
Adult-Onset Idiopathic Cervical Dystonia
Adult-onset idiopathic focal dystonia is the most common type of primary dystonia, and adult-onset idiopathic cervical dystonia (AOICD) is its most prevalent phenotype.
11
Mins
20th September 2022
Cotard’s Delusion with Sequelae of Adult Onset Failure to Thrive: A Case Report
Patients can present with chief complaints and symptoms that differ from the eventual diagnoses. The differences between aetiologies versus complications must be appreciated through careful evaluation and use of clinical investigations, laboratory testing, trial of hypotheses, and clinical gestalt.
8
Mins
22nd August 2022
Diencephalic Syndrome: Anaesthetic Management and Post-Operative Complications
Diencephalic syndrome (DS), first described by Russell in 1951, is a rare cause of failure to thrive in infants and young children with preservation of linear growth.
9
Mins
9th August 2022
Implications of the First Ex Vivo Gene Therapy Approved for Treating Early-Onset Metachromatic Leukodystrophy
MLD is caused by an accumulation of sulfatides in various organs and predominantly the central nervous system (CNS). Patients have an initial period of normal development, then experience developmental delay or stagnation (Figure 1).
11
Mins
9th August 2022
Improving The Management of Non-dystrophic Myotonia to Benefit Care Delivery and Improve Patient Outcomes
Non-dystrophic myotonias (NDM) are a group of rare muscle disorders with a reported prevalence of 0.75−1.7 per 100,000 population (Figure 1).
9
Mins
9th August 2022
Sex-Related Differences in Symptoms Among Patients Presenting with Acute Stroke: A Systematic Review and Meta-analysis
Recognising acute stroke symptoms is crucial in providing timely treatment. However, evidence suggests that females often experience unique symptoms compared with males, resulting in delays to seeking medical attention and treatment.
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