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Chronic Active Antibody-Mediated Rejection in Renal Transplant Recipients
2
Mins
April 2024
In 2022, over 92,000 kidney transplants were performed globally.1 With advancements in transplant science, 1-year graft survival rates…
Read more
8
Mins
17th May 2023
Interview: Matthew A. Sparks
Growing up, I didn’t have much exposure to medicine. There were no physicians, or even anyone in science, in my family, including…
5
Mins
9th May 2023
Interview: Sam Kant
I always enjoyed science and being part of a bigger community. Medicine combines these two aspects really well. I pursued nephrology…
12
Mins
16th March 2023
Ocedurenone: A Novel Therapy for Uncontrolled Hypertension in Advanced Chronic Kidney Disease
Setting the scene, Bakris defined CKD as a reduction in kidney function (estimated glomerular filtration rate [eGFR] <60 mL/min/1.73 m2), alongside the presence of albuminuria (≥30 mg/day) as an indication of kidney damage.
14
Mins
10th March 2023
Editor's Pick: Metabolic Acidosis in Children: A Literature Review
Metabolic acidosis is characterised by a primary decrease in the serum bicarbonate concentration, a secondary decrease in the arterial partial pressure of CO2, and a reduction in blood pH. Metabolic acidosis, acute or chronic, may have deleterious effects on cellular function and cause increased morbidity and mortality.
11
Mins
16th January 2023
Editor's Pick: Hypertension in Patients Receiving Dialysis: A Review of the Current Clinical Approach
Hypertension is a common complication in advanced chronic kidney disease (CKD), occurring in approximately 80–85% of patients. Blood…
10
Mins
19th December 2022
Prevalence of SARS-CoV-2 Cellular and Humoral Immunity Amongst Patients on Dialysis After the First Vaccination Campaign
Global immunisation against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the standard-of-care in preventing COVID-19…
5
Mins
20th September 2022
Marfan Syndrome and Autosomal Dominant Polycystic Kidney Disease: A Case of Rare Co-occurrence or Coincidence?
Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder with an incidence of 1 in 3,000–5,000.
11
Mins
20th September 2022
Findings and Implications of the REVEAL-CKD Study Investigating the Global Prevalence of Undiagnosed Stage G3 Chronic Kidney Disease
Chronic kidney disease (CKD) is a progressive condition that can lead to kidney failure and the requirement for renal dialysis or transplantation. Early-stage CKD is often missed because the disorder is initially asymptomatic; hence, many patients with CKD already have symptomatic advanced disease (Stages G4–G5) at the time of diagnosis. This is an important issue because the drugs available for the treatment of CKD are most effective when given during the early stages of the disease (Stages G1–G3).
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