Hematology

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RNA Sequencing Uncovers New Subtypes of B-cell Precursor Leukaemia

March 2025

A recent study has demonstrated how RNA sequencing can enhance the genetic classification of B-cell precursor acute lymphoblastic leukaemia patients…

Increased Cancer Risk After Cerebral Venous Thrombosis

CVT patients face a significantly higher cancer risk, especially in the first year and up to 10 years after diagnosis.

Increased Risk of Skin Cancer After Blood or Marrow Transplant

BMT survivors face a higher risk of skin cancer, with age, graft-vs-host disease, and treatment influencing outcomes.

Immune Checkpoint Inhibitor Before Allogeneic Transplant Boosts Survival in Hodgkin Lymphoma

ICI treatment before transplant enhances survival in relapsed Hodgkin lymphoma, though it increases the risk of acute GVHD.

Detectable Antibodies Lower COVID-19 Risk in Immunosuppressed

Detectable antibodies reduce COVID-19 risk in immunosuppressed individuals, emphasizing the need for tailored protection strategies.

Gene-Editing Therapy for Sickle Cell Disease Approved by NHS

The NHS has approved exa-cel, a revolutionary gene-editing therapy for sickle cell disease, offering hope for a cure.

Shared Care Model for Hematopoietic Cell Transplantation Shows Promise

Shared care after HCT improves quality of life at day 100 without affecting survival, offering a viable post-transplant model.

Key Metabolic Vulnerability in Multiple Myeloma Treatment

New research identifies VLCFA metabolism as a target to boost multiple myeloma treatment efficacy and combat drug resistance.

Molecular Dynamics Behind Different Tumour Rejection Kinetics in CAR-T Cell Therapy

A recent study has uncovered key insights into the differing tumour rejection behaviours of chimeric antigen receptor T cells (CAR-T) targeting CD19…

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