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Therapy Area
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Flagship Journal
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Interview: Niamh O'Connell
5
Mins
April 2024
When I was a medical student in the small university city of Cork, in Ireland, there was one female consultant, and she was a haematologist…
Read more
31st July 2014
Autologous Stem Cell Transplantation In Multiple Myeloma: Is It Still The Right Choice?
Autologous stem cell transplantation (ASCT) is considered the standard of care for multiple myeloma patients aged <65 years with no relevant…
31st July 2014
The Role of JAK2 Mutation in Thrombotic Complications of Chronic Myeloproliferative Neoplasms
Patients diagnosed with myeloproliferative neoplasms (MPNs) often develop thrombotic events as an onset of symptoms or in evolution. The pathogenesis of…
31st July 2014
Calreticulin in Myeloproliferative Neoplasms: The Other Side of the Alice Mirror
Calreticulin (CALR), a Ca2+ binding protein mostly localised in the endoplasmic reticulum, regulates Ca2+ homeostasis, chaperones, and other proteins to…
31st July 2014
Iron Supplementation for Perioperative Anaemia in Patient Blood Management
In patients undergoing major surgical procedures, preoperative anaemia and perioperative allogeneic blood transfusion (ABT) have been linked to increased…
31st July 2014
Looking Back To Our Roots: 80 Years of Wintrobe’s Indices
This year (2014) we are celebrating the 80th anniversary of Dr Maxwell Myer Wintrobe’s pioneer works, one of the most important contributions in clinical…
1st August 2013
Delayed Erythroid and Platelet Response to Eculizumab in Paroxysmal Nocturnal Haemoglobinuria - A Case Report and Literature Review
Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal disorder of haemopoiesis characterised by haemolytic anaemia, thrombophilia and variable…
1st August 2013
The Chemokine CCL17/TARC as a Biomarker in Hodgkin Lymphoma
Classical Hodgkin lymphoma (cHL) is a lymphoproliferative disorder hallmarked by a distinctive type of neoplastic cells, the Hodgkin and Reed/Sternberg…
1st August 2013
Pain Management in Patients with Sickle Cell Disease - A Review
Pain is defined, by the International Association for the Study of Pain (IASP), as an ‘unpleasant sensitive and emotional experience, associated with or…
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