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EMJ Dermatology 9 [Supplement 3] 2021 Feature Image
11 Mins
25 Feb 2021

Clinical Considerations Based On 5-Year Efficacy and Safety Data for the IL-23p19 Inhibitor Tildrakizumab

The indicative scaly, erythematous plaques of plaque psoriasis arise because of abnormal interactions between immune system cells and epidermal…
9 Mins
18 Feb 2021

Biological and Clinical Impacts of Ultraviolet-A on the Skin: New Insights

Terrestrial solar UVR consists of UVA (320–400 nm) and UVB (280–320 nm; typically around 295–320nm because of attenuation by the ozone…
11 Mins
10 Feb 2021

Long-term Efficacy and Safety of Tildrakizumab: 5-year Results from the reSURFACE 1 and 2 Phase III Trials in Patients with Moderate-to-severe Plaque Psoriasis

Psoriasis, a chronic systemic inflammatory disease with skin manifestations, can be an impediment to daily life. Accordingly…
8 Mins
15 Dec 2020

The Other Side of the Moon: A Clinical Dialogue on the IL-23 Pathway

Prof Reich began by highlighting how insights into the pathophysiology of psoriasis have led to the development and expansion of cytokine-targeted…
Derm 8.1 feature image
6 Mins
15 Dec 2020

Latest Highlights on Biologic Treatments for Psoriasis and Psoriatic Arthritis from EADV 2020

The VOYAGE 1 trial1 was a placebo- and active-controlled Phase III study to evaluate long-term efficacy and safety of the IL-23p19 inhibitor guselkumab…
Derm 8.1 feature image
8 Mins
15 Dec 2020

Bimekizumab Efficacy and Safety in Patients with Moderate-to-Severe Plaque Psoriasis

Psoriasis is a Th17-driven disease, with both IL-17A and IL-17F playing a pivotal role in its pathogenesis.2,3 BKZ is a monoclonal IgG1 antibody…
9 Mins
15 Dec 2020

Editor’s Pick: Managing Chronic Urticaria: Quo Vadis?

Chronic urticaria (CU) is one of the most commonly diagnosed skin conditions. CU is characterised by the presence of recurrent wheals and/or angioedema…
8 Mins
15 Dec 2020

Impaired Mitochondrial and Metabolic Function of Fibroblasts Derived from Patients with Recessive Dystrophic and Junctional Epidermolysis Bullosa

Recessive dystrophic epidermolysis bullosa (RDEB) and junctional EB (JEB) are inherited disorders characterised by fragility and blistering of epithelial…