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20 Oct 2014

Premature Heart Attacks: Bad Lifestyle, Bad Luck, or Bad Genes?

Homozygous familial hypercholesterolaemia (HoFH), a rare inherited lipid disorder usually caused by bi-allelic defects in the LDLR gene, is characterised…
20 Oct 2014

Imaging During Transcatheter Interventions for Valvular Heart Disease

Valvular heart disease is a growing field, and the number of new approaches for percutaneous treatment is increasing rapidly. These procedures usually…
20 Oct 2014

Red Cell Distribution Width for Predicting Cardiovascular Disease: A Literature Review

Although the classical risk factors for cardiovascular disease (CVD) are very important, identification of potential novel risk factors could help…
20 Oct 2014

Case Report: Double Orifice Mitral Valve with Cleft in Anterior Leaflet of Dominant Valve in an Afro-Caribbean

Double orifice mitral valve (DOMV) is a rare congenital mitral valve (MV) disorder. It is associated with other types of congenital heart disease in 45%…
20 Oct 2014

The Quest for a Medical Treatment of Aortic Stenosis: Putative Therapeutic Targets

Aortic stenosis (AS), i.e. calcification and obstruction of the aortic valve (AV), is the most common type of valvular heart disease. The therapeutic…
20 Oct 2014

Factors Affecting Serum Paraoxonase 1 Activity in Migrant and Resident Gujarati South Asians

Paraoxonase 1 (PON1) protects against the development of atherosclerosis by hydrolysing damaging lipid peroxides formed in low-density lipoprotein (LDL)…
20 Oct 2014

Rationale for Promising Novel Therapeutic Approach Focused On Endothelin Pathway for Peripheral Arterial Disease

There is evidence to suggest that endothelin (ET-1) is involved in the pathophysiology of peripheral arterial disease (PAD), contributing to…
20 Oct 2014

Current Controversies in Infective Endocarditis

Infective endocarditis (IE) remains a devastating disease with a high mortality. Its microbiology is changing with increasing incidence of Staphylococcus…