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4 Mins
11 Oct 2018

Reversal of Apixaban and Rivaroxaban Anticoagulation by Andexanet Alfa in ANNEXA-A and ANNEXA-R as Assessed by Non-Tissue Factor-Initiated Thrombin Generation Independent of Tissue Factor Pathway Inhibitor

Andexanet alfa is a modified factor Xa (FXa) drug designed to bind and sequester FXa inhibitors and thus reverse anticoagulation…
10 Mins
11 Oct 2018

Editor’s Pick: Contemporary Use of Intracoronary Imaging in Percutaneous Coronary Intervention

For >50 years, coronary angiography has been the gold standard for the assessment of coronary anatomy; however, as an isolated technique to guide the…
8 Mins
11 Oct 2018

A Comparison of Different Doses of Dexmedetomidine for Myocardial Protection in Percutaneous Coronary Interventional Patients

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. Myocardial injury in acute MI is due to both ischaemic as well…
10 Mins
11 Oct 2018

Cardioprotective Approaches to the Management of Patients with Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Do We Need Increased Surveillance in Elderly Women on Trastuzumab?

Due to recent advances in antineoplastic treatment for breast cancer, cancer-related mortality has substantially decreased. However, several systemic…
7 Mins
11 Oct 2018

The Cardiomyopathy of Iron Deficiency Anaemia

Anaemia is a significant challenge in global health; it is characterised by lower than normal levels of red blood cells and haemoglobin per unit volume…
13 Mins
11 Oct 2018

Treatment of Chronic Chagasic Patients: Is Killing the Parasite the Only Option?

Chronic Chagasic cardiomyopathy (CCC) is one of the principal challenges for clinicians treating asymptomatic Chagasic patients. Only benznidazole (BZ)…
6 Mins
1 Mar 2018

Current Approach to the Treatment of Coronary Chronic Total Occlusions

Coronary chronic total occlusions (CTO), in spite of excellent progress in the field of medicine, remain a great challenge for interventional cardiologists.
6 Mins
1 Mar 2018

Positive Vessel Remodelling

Since its introduction, the success of percutaneous transluminal coronary angioplasty (PTCA) has been jeopardised by recoil, neointima proliferation, and…