A NEW study revealed a significant impact of chronic endometritis (CE) on pregnancy outcomes in women with endometriosis-associated infertility (EMS), revealing a dual narrative of improved pregnancy rates but elevated risks of complications.
The retrospective cohort study analysed data from 685 patients with EMS, of whom 46.42% were diagnosed with CE. While advanced treatment techniques like combined hysteroscopy and laparoscopy were associated with higher pregnancy rates, particularly in patients with an Endometriosis Fertility Index (EFI) score of 7–10, CE was found to markedly increase risks of adverse pregnancy outcomes.
Notable complications included placenta previa (13.01%), gestational hypertension (5.69%), and caesarean delivery (59.34%) among EMS patients with CE. These findings call for more vigilant monitoring and specialised care to manage these heightened risks.
The study sheds light on the complex interplay between CE and EMS, suggesting that while certain interventions can improve fertility, careful management of pregnancy complications is crucial for optimal outcomes. As CE continues to present challenges in the reproductive health of individuals with EMS, personalised care strategies could be key to improving both fertility and safety.
Reference
Lin S et al. How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study. Reprod Health. 2024;DOI: 10.1186/s12978-024-01897-9.