Onc Now | Episode 13
In this episode of Onc Now, host Jonathan Sackier is joined by Sebastian Stintzing, Head of Department of Medicine, Division of Hematology, Oncology, and Cancer Immunology, Charité – Universitäetsmedizin Berlin, Germany. They discuss the most promising developments in gastrointestinal oncology, with particular focus on the role of personalised medicine in metastatic colorectal cancer treatment.
Spotify | Apple | Amazon Music | Youtube | Download MP3 (47 mins)
Sebastian Stintzing is an established name in the field of oncology and serves as Head of the Department of Medicine, Division of Hematology, Oncology, and Cancer Immunology at Charité – Universitätsmedizin in Berlin. With a special focus on gastrointestinal oncology, particularly metastatic colorectal cancer, Professor Stintzing leads groundbreaking research into clinical outcomes and biomarker-driven treatments. He’s also held esteemed positions across multiple top universities, including the USC Norris Comprehensive Cancer Center, Keck Medical School University of Southern California, where he worked as a research fellow, and the University of Munich, where he acted as Associate Professor.
Timestamps:
00:00 – Introduction
03:04 – Impactful developments in gastrointestinal oncology
08:53 – Issues with funding clinical trials
14:17 – Designing trials and the importance of patient advocacy
17:11 – Translational biomarker programs
19:58 – Treatment strategies for RAS wild-type tumours
22:28 – The FIRE-4.5 study on mutant metastatic colorectal cancer
29:50 – Genetic profiling and epigenomics
33:12 – Precision medicine and immune oncology in GI cancers
34:52 – Colorectal cancer in younger adults
34:54 – Raising awareness for early screening of GI cancers
