Decoding Epilepsy: Innovations, Misdiagnoses, and Game-Changing Therapies - European Medical Journal

Decoding Epilepsy: Innovations, Misdiagnoses, and Game-Changing Therapies

Neurology

The EMJ Podcast | Episode 242

This week, Jonathan sits down with Jacqueline French to explore groundbreaking innovations in epilepsy research, the challenges of misdiagnosis, and the transformative impact of advancements in clinical trial methodologies. French also shares insights into global epilepsy care challenges, and her vision for the future of neurological health. 

Spotify | Apple | Amazon Music | Download MP3 (49 mins)

Speaker bio: 

Jacqueline French Headshot

Jacqueline French, Professor of Neurology at NYU Langone Health’s Comprehensive Epilepsy Center, and Founder/Director of the Epilepsy Study Consortium.   

Jacqueline trained in neurology at Mount Sinai Hospital in New York, USA, and did her fellowship training in electroencephalography and epilepsy at Mount Sinai Hospital and Yale University. She has focused her research efforts on developing novel therapeutics for epilepsy and new methodologies for clinical trials, and has been active in creating guidelines for the American Academy of Neurology (AAN) and the International League Against Epilepsy. She is the past president of the American Epilepsy Society (AES), and chaired an AAN/AES committee that produced two widely quoted guidelines on the use of new antiepileptic drugs.   

Timestamps:
  • 00:00 – Introduction
  • 01:34 – Career beginnings
  • 07:38 – The Epilepsy Study Consortium
  • 14:48 – Ethical considerations in clinical trials
  • 17:13 – New strategies for designing trials
  • 25:25 – The evolving landscape of anti-seizure drugs
  • 27:45 – Innovative treatments
  • 32:30 – Cases of misdiagnosis
  • 35:19 – The five S’s to identify epilepsy
  • 39:12 – Educating and tackling stigma
  • 44:03 – French’s three wishes for healthcare

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