Dravet syndrome and Lennox–Gastaut syndrome are types of developmental and epileptic encephalopathies (DEE) that manifest in childhood. Non-seizure symptoms (NSS) in these patients can range from learning and behavioural impairments, to motor and eating difficulties. This article covers an insightful industry-sponsored symposium, chaired by Helen Cross, Director, University College London (UCL) Great Ormond Street Institute of Child Health, UK; Elaine Wirrell, Chief of Child Neurology, Mayo Clinic, USA; and Kette Valente, Full Professor of Pediatric Neurobiology, University of São Paulo, Brazil. These experts in epilepsy discuss the various methods of assessing and measuring NSS, and how this may lead to a better understanding of the patient’s burden beyond seizures.
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