A NOVEL endoscopic closure technique using a long transparent cap has shown promise as a fast and effective method for sealing gastrointestinal (GI) defects following tumour resection, according to a new study.
The study, conducted at the First Affiliated Hospital of Zhengzhou University, retrospectively analysed clinical data from patients who underwent endoscopic resection for gastric submucosal tumours between January 2020 and November 2023. Researchers compared outcomes between two closure techniques: the newly developed Long Transparent Cap-Assisted Clip Closure (LTCCC) and the traditional Purse-String Suture (PSS) method.
While both groups achieved a 100% wound closure success rate, the LTCCC technique significantly reduced procedure time, averaging 17.4 minutes compared to 28.8 minutes in the PSS group (P <0.001). No significant differences were observed in postoperative hospital stays or adverse events, and both techniques demonstrated excellent healing with no tumour recurrence or complications, such as fistulas or sinuses, during a median follow-up of 32 months.
The study highlights LTCCC as a simple, safe, and time-efficient alternative for GI defect closure following endoscopic tumour resection. Its potential to streamline endoscopic procedures without compromising outcomes could make it a valuable addition to clinical practice.
Aleksandra Zurowska, EMJ
Reference
Dai N et al. Long transparent cap-assisted clip closure technique: a new choice for gastrointestinal defect closure. BMC Gastroenterol. 2025;DOI: 10.1186/s12876-025-03717-1.
