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5 Mins
27 Jul 2023

Proteinuria as a Surrogate Endpoint for Disease Progression in IgA Nephropathy: Predicting Long-Term Treatment Effects of Sparsentan

IgA nephropathy (IgAN) is a rare, life-limiting disease for which there is significant unmet need. Until recently, drug development for…
8 Mins
27 Jul 2023

Interview: Catherine Quinlan

I only ever wanted to be a paediatrician, thanks to ER’s Doug Ross, and my first job was on the nephrology service in Temple Street…
11 Mins
27 Jul 2023

Recent Advances in Targeting Complement in Glomerular Disease

The complement system has been an appealing drug target for a long time. However, early drug development efforts have failed for…
10 Mins
27 Jul 2023

The Effect of Tip Placement on Fibrin Sheath Formation in Poorly Functioning Tunnelled Haemodialysis Lines

One of the most common causes of a poorly functioning haemodialysis (HD) line is the formation of a fibrin sheath. Tunnelled HD lines contain a Dacron® (Invista, Wichita, Kansas, USA) cuff at the skin entry site, which helps secure the catheter in place due to the fibrosis that occurs in the subdermal tissues.
6 Mins
19 Jul 2023

Steroid-Dependent Nephrotic Syndrome in a Child After an Allogeneic Bone Marrow Transplant: A Case Report

The authors present a case report of a child presenting with difficult-to-manage, steroid-sensitive, frequently relapsing nephrotic…
5 Mins
14 Jul 2023

A Case Control Study of Mesoamerican Nephropathy in Farmers with Long-Term Exposure to Agrochemical Compounds in El Salvador

Chronic kidney diseases (CKD) are very prevalent in Central America, particularly in El Salvador. Mesoamerican nephropathy (MN) is a CKD diagnosis that almost exclusively affects young male agricultural labourers.
16 Mins
14 Jun 2023

Anaemia of Chronic Kidney Disease: Aligning Patient and Physician Awareness - Interviews with Three Key Opinion Leaders and Patient Advocates

Anaemia is a common and serious complication of chronic kidney disease (CKD) that can greatly impact the daily lives of patients. However…
8 Mins
6 Jun 2023

Editor's Pick: Relationships of Chronic Kidney Disease and Thyroid Dysfunction in Patients with Stage 4 and 5 Chronic Kidney Disease: A Cross-Sectional Study

A spectrum of various pathophysiological processes associated with a progressive worsening in estimated glomerular filtration rate (eGFR)…