Role of Coagulation Factor Concentrates in the Operating Room - European Medical Journal

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Role of Coagulation Factor Concentrates in the Operating Room

Hematology
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Authors:
*Cheng-Hock Toh,1,2 Yasir Alhamdi1

1. Institute of Infection and Global Health, University of Liverpool, Liverpool, UK
2. Roald Dahl Haemostasis and Thrombosis Centre, Royal Liverpool University Hospital, Liverpool, UK
*Correspondence to [email protected]

Disclosure:

The authors have declared no conflicts of interest.

Received:
24.05.16
Accepted:
19.08.16
Citation:
EMJ. ;1[4]:98-105. DOI/10.33590/emj/10313464. https://doi.org/10.33590/emj/10313464.
Keywords:
Fibrinogen concentrate, fresh frozen plasma (FFP), prothrombin complex concentrate (PCC), coagulation monitoring, surgery

Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.

Abstract

The use of fresh frozen plasma, cryoprecipitate, and platelets has been the mainstay of approaches to correct coagulopathies that can arise in the perioperative setting. Limitations include the time delay from obtaining results of coagulation screens to the availability of thawed fresh frozen plasma and the potential of fluid overload. With advances in both global haemostatic testing and concentrates of coagulation factors, there are increasing opportunities for innovative practice. However, there remains a paucity of studies that can provide good quality, unbiased evidence. These issues are elaborated here to form the basis for future study.

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