Managing Ulcerative Colitis: The Guidelines and Beyond - European Medical Journal

Managing Ulcerative Colitis: The Guidelines and Beyond

Gastroenterology
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Authors:
Mitchell RKL Lie, C Janneke van der Woude
Disclosure:

No potential conflict of interest.

Received:
17.09.13
Accepted:
19.11.13
Citation:
EMJ Gastroenterol. ;[1]:82-91. DOI/10.33590/emjgastroenterol/10312665. https://doi.org/10.33590/emjgastroenterol/10312665.
Keywords:
Ulcerative colitis, management, therapy, 5-ASA, corticosteroids, azathioprine, 6-mercaptopurine, 6-thioguanine, cyclosporine, tacrolimus, methotrexate, mycophenolate mofetil, infliximab, adalimumab, golimumab, vedolizumab

Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.

Abstract

Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the use of 5-ASA, corticosteroids, thiopurines, cyclosporine, and anti-TNFα therapies. However, guidelines do have some drawbacks, mainly a lack of concrete advice concerning patients resistant to these aforementioned therapies. This review gives a short overview of current guidelines and addresses treatment alternatives for conventional therapies.

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