European Archives - Page 577 of 899 - European Medical Journal

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2 Mins
17th July 2018

Microcrystalline Tyrosine: An Appropriate Alternative to Aluminium as Adjuvant in Vaccines and Allergen Immunotherapy

Adjuvants are compounds added to antigens in vaccines to increase the body’s immune response to an antigen.1 Similarly, adjuvants are added to allergens…
8 Mins
17th July 2018

Raising the Clinical Bar Beyond Current Biologics in Uncontrolled Persistent Asthma: Translating Emerging Data in Future Clinical Decisions

Asthma is a heterogeneous disease with multiple phenotypes, caused by a complex interplay of inflammatory pathways. Up to 70% of patients with asthma…
1 Mins
17th July 2018

Allergy Prevention by Allergens Depends on Their Ligands

The prevalence of allergy in the Western world is increasing, with 35% of women and 24% of men in Germany affected.1 It is unclear why atopic individuals…
8 Mins
17th July 2018

Editor’s Pick: Asthma and Food Allergies

There is a long-established link between allergic diseases in atopic individuals, whereby having one atopic condition can predispose that individual to…
1 Mins
17th July 2018

Response to Omalizumab in Urticaria and Asthma: Is it a ‘Lifetime Together’ Treatment?

Omalizumab is a recombinant human monoclonal antibody that blocks the immunoglobulin (Ig)E receptor and is indicated in cases of severe asthma (SA)…
9 Mins
17th July 2018

The Oligosaccharide Galactose-α-1,3-Galactose and the α-Gal Syndrome: Insights from an Epitope that is Causal in Immunoglobulin E-Mediated Immediate and Delayed Anaphylaxis

Galactose-α-1,3-galactose (α-Gal) is an oligosaccharide that was first described as a cause of immunoglobulin E-mediated anaphylaxis in cases of…
1 Mins
17th July 2018

Use of Breathomics in the Diagnosis of Paediatric Patients with Persistent Asthma

In paediatric asthma, symptoms tend to appear during the first 6 years of life and may be associated with different disease phenotypes and endotypes, each…
9 Mins
17th July 2018

Allergy to Stinging Insects: Diagnosis and Management

Stinging insects that cause allergic reactions belong to the order Hymenoptera, which includes wasps, hornets, bees, yellow jackets, true hornets, and…
2 Mins
17th July 2018

Malignancies as the Main Cause of Death in Common Variable Immunodeficiency: An Italian Multicentre Study

Cancer immunosurveillance is a major function of the immune system. Strong evidence for the role of the immune system in antitumour surveillance…
9 Mins
17th July 2018

Autoinflammatory Diseases: Consequences of Uncontrolled Inflammasome Activation

Inflammasomes are sensors within the innate immune system that are responsible for the regulation of caspase-1 activation and the initiation of…