European Archives - Page 485 of 900 - European Medical Journal

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8 Mins
12th November 2019

PARP Inhibitors as a Novel Treatment Strategy for Patients with BRCA-Mutated Metastatic Breast Cancer

Physiologically, cells are equipped with DNA damage repair systems that can correct various errors…
3 Mins
12th November 2019

Branchial Cleft Cyst – A Misdiagnosed Developmental Anomaly

The branchial cleft’s embryological journey begins between the first 3–8 weeks of intrauterine life. Five mesodermal arches form by the inpouching…
2 Mins
12th November 2019

Measuring the Cancer Burden in Europe: the European Cancer Information System (ECIS)

Cancer is the second leading cause of mortality in European Union (EU) Member States,1 with more than 1.4 million deaths…
1 Mins
12th November 2019

Phase I Combination Dose-Finding and Phase II Expansion Cohorts of Lenvatinib with Etoposide and Ifosfamide in Patients Aged 2 to ≤25 Years with Relapsed or Refractory Osteosarcoma

Osteosarcoma is the most common primary bone tumour in adolescents and young adults, with no survival improvement in the last few decades…
9 Mins
12th November 2019

Discovery of a ‘Grail-Shaped’ Drug: Ne-ratinib and the Downregulation of Mutant RAS

The drug neratinib (HKI-272, Nerlynx®) was originally developed by Wyeth Research Laboratories, with its initial characterisation published in 2004…
11 Mins
12th November 2019

Optimised Tumour Sampling and Processing by a Multidisciplinary Approach for an Accurate Diagnosis in Non-Small Cell Lung Cancer

In the era of target and immunotherapy, the multidisciplinary approach of lung cancer is now mandatory. Close collaboration between pulmonologists…
7 Mins
12th November 2019

Follow-Up of Accessory Breast Cancer Patient: Case Report

Accessory breast is a congenital atavism condition. Accessory breast tissue may arise anywhere along the mammary line because of the failure of complete…
November 2019

EMJ Oncology 7.1 2019

This edition of EMJ Oncology 7.1 offers to the readers a wide range of topics and papers in relation to cancer diagnosis and management…
9 Mins
6th November 2019

Hepatitis B Care Pathway in the United Arab Emirates: Current Situation, Gaps, and Actions

This paper aims to assess the current situation of the HBV care pathway in the United Arab Emirates (UAE), identify gaps and barriers therein…
November 2019

EMJ Diabetes 7.1 2019

Our newest edition EMJ Diabetes 7.1 provides a compendious review of the congress, along with a selection of peer-reviewed articles and interviews…