Drug resistance among patients with tuberculosis (TB) is an emergent topic that requires intervention. According to a survey of TB drug resistance in India, resistance to any fluoroquinolones (FQ) reported in cases of multidrug resistance (MDR) to TB was 21.82%.

This infographic explores the diversity of patient populations in US clinical trials and the pharmaceutical industry’s efforts to address this and improve outcomes.

Hannah Gower | Cardiology and Internal Medicine Speciality Registrar, Royal Cornwall Hospitals NHS Trust, UK

Histotripsy is a non-invasive, non-thermal, and non-ionising focused ultrasound (US) treatment method that destroys tissue through mechanical disruption caused by cavitation. Short-duration (<20 μs) high-pressure US pulses cause the rapid expansion and collapse of endogenous gas bubbles in targeted tissue.

Juan Gómez Rivas | Urology Consultant, Hospital Clinico San Carlos, Madrid, Spain; Assistant Professor, Universidad Complutense de Madrid, Spain

Cholestatic liver diseases include primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and progressive familial intrahepatic cholestasis (PFIC). In all of these conditions, cholestatic itch is a major symptom that can severely and chronically impact a person’s quality of life (QoL).