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16th December 2013

Endoscopic Optical Enhancement Technologies in IBD

Optical enhancement technologies are emerging as promising tools to improve diagnosis and clinical management of patients with IBD.
16th December 2013

Adhesion Molecules as a Therapeutic Target in IBD

Recruitment of circulating leukocytes to areas of inflammation is a key process in the pathophysiology of inflammatory bowel diseases, including…
16th December 2013

Effects of Antibiotic Use on the Microbiota of the Gut and Associated Alterations of Immunity and Metabolism

The excessively widespread use of antibiotics has created many threats. A well-known problem is the increasing bacterial resistance to antibiotics…
16th December 2013

Managing Ulcerative Colitis: The Guidelines and Beyond

Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the…
16th December 2013

Non-Surgical Therapy for Unresectable Hilar Cholangiocarcinoma

Hilar cholangiocarcinoma (HCCA) is characterised by late clinical symptoms. As a consequence, most patients will not undergo surgery, and palliation is…
16th December 2013

Endoscopic Necrosectomy as Treatment for Infected Pancreatic Necrosis

Necrotising pancreatitis can be life-threatening, but the introduction of endoscopic necrosectomy has led to a tremendous reduction of lethality.
16th December 2013

The Versatile Role of the Vagus Nerve in the Gastrointestinal Tract

The vagus nerve, the major nerve of the parasympathetic nervous system, innervates several organs from the neck to the abdomen. The vagal branches…
16th December 2013

A Review of Crohn’s Disease

Crohn’s disease is a chronic relapsing inflammatory bowel disease that may affect any part of the gastrointestinal tract. The ileum, colon, and perineum…
11th December 2013

Resistance to Targeted Therapies in Melanoma: New Insights

Several molecular mechanisms are involved in melanoma genesis and progression. Molecular targets for effective therapeutic intervention have been…
11th December 2013

Skin Reactions Secondary to Anticancer Agents

In recent decades, new chemotherapeutic agents have been introduced in cancer therapy. The skin is often the target for their toxicity.