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1st August 2013

The Chemokine CCL17/TARC as a Biomarker in Hodgkin Lymphoma

Classical Hodgkin lymphoma (cHL) is a lymphoproliferative disorder hallmarked by a distinctive type of neoplastic cells, the Hodgkin and Reed/Sternberg…
1st August 2013

Pain Management in Patients with Sickle Cell Disease - A Review

Pain is defined, by the International Association for the Study of Pain (IASP), as an ‘unpleasant sensitive and emotional experience, associated with or…
1st August 2013

Treatment of HIV-Associated Burkitt Lymphoma

Burkitt lymphoma (BL) is a highly aggressive B-cell malignancy, occurring with increased frequency among patients infected with HIV. For several years…
1st August 2013

RNA Interference (RNAi): An Effective Way to Develop Rational Combination Therapies with Hypomethylating Agents in Acute Leukaemias and Myelodysplastic Syndrome

Therapeutic progress in aggressive myeloid malignancies such as acute myeloid leukaemia (AML), myelodysplastic syndrome (MDS) and advanced…
1st August 2013

Preventing Infections in Higher-Risk Myelodysplastic Syndrome Patients Treated with Hypomethylation Agents

Hypomethylation agents became the standard of care for patients with high-risk myelodysplastic syndrome (MDS). While long-term benefits of azacitidine…
1st July 2013

The Evolving World of Chronic Kidney Disease Mineral Bone Disorder

Chronic kidney disease – mineral and bone disorder (CKD-MBD) is associated with a significant morbidity and mortality. In vitro and animal models suggest…
1st July 2013

Clinical Proteomics: The Potentiality of Urine Analysis for Understanding Diabetic Nephropathy

The incidence of diabetic nephropathy (DN) is constantly rising in parallel with the prevalence of type 2 diabetes and has been predicted to double…
1st July 2013

Treatment of Antibody-Mediated Rejection in Kidney Transplantation

Antibody-mediated rejection (AMR) is a relatively rare but severe complication in kidney transplantation associated with increased risk of graft loss.
1st July 2013

Vascular Calcification in Chronic Kidney Disease: An Update

Vascular calcification involves passive degeneration and an active process of arterial mineralisation, resembling osteogenesis. In chronic kidney disease…
1st July 2013

‘A Better Way to Measure Choices’ Discrete Choice Experiment and Conjoint Analysis Studies in Nephrology: A Literature Review

Discrete choice experiments (DCE) and conjoint analysis (CA) are increasingly used to address health policy issues. This is because the DCE and CA…