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Therapy Area
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Allergy & Immunology
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Flagship Journal
Gastroenterology
General Healthcare
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Videos
Oncology
26 Jun 2015
Updated results from the SORAML trial of sorafenib in younger patients with newly diagnosed AML
The randomised, controlled phase 2 SORAML trial showed that the addition of the tyrosine kinase inhibitor, sorafenib, to chemotherapy improved event-free…
Hematology
26 Jun 2015
The crucial roles of GFI1B in platelet development
The identification of eight new Growth Factor Independence 1B (GFI1B) variants in families with bleeding and platelet disorders may result in the…
Hematology
26 Jun 2015
Pacritinib therapy led to symptom improvement in myelofibrosis
The phase 3 PERSIST-1 study showed that pacritinib, a selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3), is more…
Hematology
26 Jun 2015
Treatment and outcome of CML patients from the EUTOS population-based registry
The European Treatment Outcome Study (EUTOS) investigated the treatment and treatment outcome of patients with chronic myeloid leukaemia (CML).
Hematology
26 Jun 2015
Venetoclax (ABT-199/GDC-0199) plus rituximab shows promise in relapsed/refractory CLL
n a phase 1b, open-label, dose-escalation, multicentre study of patients with relapsed or refractory chronic lymphocytic leukaemia (CLL), the combination…
Hematology
26 Jun 2015
Adding elotuzumab to standard treatment for myeloma reduced disease progression
ELOQUENT-2, a phase 3, randomised, open-label study of lenalidomide and dexamethasone with or without elotuzumab in patients with relapsed or refractory…
Oncology
26 Jun 2015
Phase 3 CheckMate 067 trial of nivolumab in previously untreated advanced melanoma
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, James Larkin, FRCP, PhD, Consultant Medical Oncologist at The Royal Marsden…
Oncology
26 Jun 2015
Whole Brain Radiation Therapy is More Harmful Than Beneficial for Small Brain Metastases
In the phase 3 NCCTG N0574 (Alliance) trial, patients with 1 to 3 small brain metastases were randomised to receive stereotactic radiosurgery (SRS) alone…
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