Articles

Cancer cachexia is highly prevalent among patients with the advanced stages of cancers, affecting an estimated 12 million people worldwide and…

Chronic inflammation is the single major contributor to the pathogenesis of sigmoid colon inflammatory diseases such as segmental colitis associated disease and inflammatory bowel disease (IBD)

There is mounting evidence of an associative link between inflammatory bowel disease (IBD) and clinical depression…

Inflammatory bowel disease, consisting of Crohn’s disease and ulcerative colitis, causes chronic gastrointestinal symptoms and can lead to morbidity and mortality if uncontrolled or untreated.

Colonic perforation post colonoscopy is rarely seen; however, when coupled with massive pneumoperitoneum in haemodynamically stable patients,

Achalasia cardia is the best characterised oesophageal motility disorder. It is characterised by progressive ganglion cell degeneration in the oesophageal myenteric plexus, which results in impaired lower oesophageal sphincter (LES) relaxation upon swallowing and aperistalsis in the distal smooth muscle segment of the oesophagus.

Acute kidney injury is a frequent complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), principally because of hypotension and…

In Part One of this narrative review examining the pathogenesis of severe coronavirus disease (COVID-19), the author addressed the mechanism by which the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus subverts the innate immune response while remaining largely invulnerable to its effector functions…