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Rheumatology
25 Jul 2014

Update on Genetic Susceptibility and Pathogenesis in Juvenile Idiopathic Arthritis

Juvenile idiopathic arthritis (JIA) is a multifactorial disease with a pathogenesis which remains inexplicable. However, genome-wide association studies…
Rheumatology
25 Jul 2014

The Importance of the mTOR Regulatory Network in Chondrocyte Biology and Osteoarthritis

Osteoarthritis (OA) is a chronic disorder associated mainly with pain, limited range of motion, stiffness, joint inflammation, and articular cartilage…
Rheumatology
25 Jul 2014

Why Basic Calcium Phosphate Crystals Should Be Targeted In the Treatment of Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and results in significant social, psychological, and economic costs. It is characterised by…
Rheumatology
25 Jul 2014

Extra-Articular Manifestations of Rheumatoid Arthritis, Now

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease, characterised by polyarthritis and extra-articular organ disease, including…
Rheumatology
25 Jul 2014

Antiphospholipid Syndrome Novel Therapies

Antiphospholipid syndrome (APS) is an autoimmune disease characterised by arterial and/or venous thrombosis, recurrent pregnancy loss, and persistently…
Nephrology
18 Jul 2014

Pain in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder affecting 1 in 1,000 people and is responsible for 10% of cases of…
Nephrology
18 Jul 2014

Autosomal Dominant Polycystic Kidney Disease: Review and Management Update

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal…
Nephrology
18 Jul 2014

Chronic Kidney Disease – Where Next? Predicting Outcomes and Planning Care Pathways

With the introduction of the National Kidney Foundation Kidney Disease Outcomes Quality Initiative chronic kidney disease (CKD) guidelines, CKD has been…