Articles

Patients diagnosed with myeloproliferative neoplasms (MPNs) often develop thrombotic events as an onset of symptoms or in evolution. The pathogenesis of…

Calreticulin (CALR), a Ca2+ binding protein mostly localised in the endoplasmic reticulum, regulates Ca2+ homeostasis, chaperones, and other proteins to…

In patients undergoing major surgical procedures, preoperative anaemia and perioperative allogeneic blood transfusion (ABT) have been linked to increased…

This year (2014) we are celebrating the 80th anniversary of Dr Maxwell Myer Wintrobe’s pioneer works, one of the most important contributions in clinical…

Despite not knowing much about biology, and being able to successfully treat very few diseases, doctors in the 19th century were held in very high regard.

Systemic sclerosis (SSc) is an autoimmune disease in which vascular damage and immune activation leads to excessive accumulation of extracellular matrix…

Idiopathic scoliosis (IS) is a lifetime condition and is defined as a structural, lateral rotated curvature of the spine of >10° on standing coronal…

Osteoporosis is one of the leading causes of handicap worldwide and a major contributor to the global burden of diseases. In particular, osteoporosis is…