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Neurology
10 Mins
7 Aug 2018

Editor's Pick: Palliative Care in Neurology: Integrating a Palliative Approach to Amyotrophic Lateral Sclerosis Care

This narrative review examines connections between neurology, specialist palliative care, and an integrated palliative approach to care for people living…
Neurology
10 Mins
7 Aug 2018

Behçet’s Disease and Neuro-Behçet’s Syndrome

Behçet’s disease is an idiopathic chronic relapsing multisystem vascular-inflammatory disease of unknown origin, which usually presents with orogenital ulceration and uveitis and is identified as the triple-symptom complex.
Neurology
9 Mins
7 Aug 2018

Spatial Patterns of the Tau-Immunoreactive Inclusions in Eight Different Tauopathies are Consistent with the Spread of Pathogenic Tau

Tauopathies are a major group of neurodegenerative disorders characterised by the presence of tau-immunoreactive inclusions in the cytoplasm of neurons…
Neurology
9 Mins
7 Aug 2018

Plasmapheresis for Neuromyelitis Optica: A Review from the Transfusion Medicine Specialist’s Perspective

Neuromyelitis optica is characterised by severe visual impairment and neurologic dysfunction, and aggressive plasmapheresis treatment is often recommended.
Hematology
9 Mins
2 Aug 2018

Editor's Pick: Allogeneic Haematopoietic Stem Cell Transplantation for Chronic Myeloid Leukaemia in the Era of Tyrosine Kinase Inhibitors

The introduction of tyrosine kinase inhibitors (TKI) has dramatically improved the prognosis of chronic myeloid leukaemia (CML) patients and, therefore…
Hematology
10 Mins
2 Aug 2018

Therapeutic Options in Myelodysplastic Syndromes: Established and Emerging Therapies

Although hypomethylating agents (HMA) have revolutionised the treatment of myelodysplastic syndromes (MDS), a significant proportion of patients either…
Hematology
11 Mins
2 Aug 2018

Making Rituximab Directly Cytotoxic for Substantial Improvement in Therapeutic Efficacy

The humanised anti-CD20 antibody (Ab) rituximab (RTX) has significantly improved the prognosis of B cell non-Hodgkin’s lymphomas (BNHL). However, major…
Hematology
12 Mins
2 Aug 2018

Staging of Mycosis Fungoides and Sézary Syndrome: Time for an Update?

Mycosis fungoides is the most common variant of cutaneous T cell lymphoma and frequently presents as early-stage disease with skin patches and plaques with an indolent course, but patients experience significant morbidity from itch and disfigurement.