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Gastroenterology
2 Mins
11 Dec 2018

Predictive Value of PAGE-B Score in Tunisian Patients with Chronic Hepatitis B Treated with Entecavir

Current first-line oral nucleos(t)ide analogues, entecavir (ETV) and tenofovir, have had a major impact on chronic hepatitis B virus (HBV) (CHB) treatment.
Gastroenterology
1 Mins
11 Dec 2018

Diagnostic and Prognostic Values of Both S100 Calcium Binding Protein A4 (S100A4) and Glypican 3 in the Tissues of Hepatocellular Carcinoma in Egyptian Cirrhotic Hepatitis Virus C Patients: A Tissue Microarray-Based Study

The S100 protein family is a multigenic group of non-ubiquitous, cytoplasmic, EF-hand, Ca2+-binding proteins, sharing significant structural similarities…
Gastroenterology
2 Mins
11 Dec 2018

Bowel Preparation for Small Bowel Capsule Endoscopy: Better Late than Never

Since the turn of the millennium, small bowel capsule endoscopy (SBCE) has become the preferred method for investigating the small bowel, namely in cases…
Gastroenterology
1 Mins
11 Dec 2018

Outlet Dysfunction is Prevalent in Severe Functional Bloating: A Prospective, Multicentre, Italian Study

Our research objective was to investigate the relationship between the defecation pattern, the severity of bloating, and the abdominal girth changes in…
Gastroenterology
1 Mins
11 Dec 2018

Safety and Rate of Delayed Adverse Events with Lumen-Apposing Metal Stents for Pancreatic Fluid Collections: A Multicentre Study

Endoscopic transmural drainage of symptomatic pancreatic fluid collections (PFC) using lumen-apposing metal stents (LAMS) has become common practice…
Gastroenterology
2 Mins
11 Dec 2018

Acetic Acid-Guided Biopsies Versus Mapping Biopsies for Barrett’s Surveillance: The ABBA Study

Barrett’s surveillance currently involves untargeted mapping biopsies; however, this procedure can still miss certain pathologies…
Oncology
2 Mins
6 Dec 2018

First In-Human Study with GSK3359609, an Inducible T cell Costimulator Receptor Agonist in Patients with Advanced, Solid Tumours: Preliminary Results from INDUCE-1

Inducible T cell costimulator (ICOS), a member of the CD28/B7 receptor superfamily, is expressed on T cells after T cell receptor engagement with cognate…
Oncology
1 Mins
6 Dec 2018

Preliminary Safety, Efficacy, and Pharmacokinetic and Pharmacodynamic Characterisation from GARNET, a Phase I Clinical Trial of the Anti-PD-1 Monoclonal Antibody TSR-042 in Patients with Recurrent or Advanced Microsatellite Instability-High Endometrial Cancer

At the European Society for Medical Oncology (ESMO) 2018 Congress, data from the ongoing Phase I clinical trial of the anti-programmed death…