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Nephrology
1 Mins
30 Jul 2019

Hungarian Vasculitis Registry: Results of the First Five Years

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare systemic autoimmune disease with a yearly incidence rate of around 20…
Nephrology
1 Mins
30 Jul 2019

Allo-Haemodialysis as a Novel Renal Replacement Modality: Urea Kinetics in a Paediatric Use Case

Lack of affordable renal replacement therapy (RRT), especially in limited resource settings, puts patients with kidney failure at the risk of imminent…
Nephrology
2 Mins
30 Jul 2019

Kt/V Achievement and Mortality in Haemodialysis Patients in the Gulf Cooperation Council (GCC) Countries: Results from DOPPS (2012-2018)

Adequate dialysis, as measured by Kt/V, is important for maintaining good health in haemodialysis (HD) patients. Guidelines recommend single pool Kt/V…
Nephrology
2 Mins
30 Jul 2019

Changes in Intraocular Pressure During Haemodialysis and the Role of Ultrafiltration Rate

Ocular problems have been reported to exist in patients with end-stage renal disease (ESRD). Discounting ageing itself, which is a known risk factor…
Nephrology
1 Mins
30 Jul 2019

Changes of Salivary Creatinine and Urea in Animal Models of Kidney Disease

Plasma creatinine and urea are widely used as markers of renal function. Saliva is an alternative diagnostic fluid with many advantages in comparison…
Nephrology
2 Mins
30 Jul 2019

Impact of Chronic Kidney Disease on the Drugs Eliminated Predominantly Through a Non-Renal Route: A Proof of Concept Study with Citalopram

Drug dosing in patients with chronic kidney disease (CKD) can be challenging due to the exclusion of such patients in the clinical trials during the drug…
Nephrology
1 Mins
30 Jul 2019

A Novel Mechanism of Diclofenac’s Action: Inhibition of Kynurenic Acid Production in Rat Kidney In Vitro

Non-steroidal anti-inflammatory drugs (NSAID) are one of the most popular analgesics due to their efficacy and availability over the counter.1 However…
Rheumatology
1 Mins
29 Jul 2019

Efficacy and Safety of E6011, an Anti-Fractalkine Monoclonal Antibody, in MTX-IR Patients with Rheumatoid Arthritis

Fractalkine (CX3CL1, designated as FKN hereafter) is the sole member of the CX3C chemokine family which leads to dual actions, chemotaxis, and cell…