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14 Jul 2015

IgA Nephropathy: New Aspects in Pathophysiology and Pathogenesis

Knowledge of the pathophysiology of immunoglobulin A nephropathy (IgAN) has progressed significantly, with this disease being clearly identified as an…
14 Jul 2015

Primary Focal Segmental Glomerulosclerosis: Why Are Pieces of This Puzzle Still Missing?

Focal segmental glomerulosclerosis (FSGS) can be classified as primary or secondary. Moreover, many causes of primary FSGS have been identified in recent…
14 Jul 2015

Chronic Kidney Disease and Endothelium

The endothelial cell layer is responsible for molecular traffic between the blood and surrounding tissue, and endothelial integrity plays a pivotal role…
3 Dec 2014

Understanding Exercise-Associated Hyponatraemia: From Pathophysiology to Treatment

The practice of extreme sports is becoming more and more common. Despite physiological adaptation, people who intensively exercise are exposed to…
18 Jul 2014

Diagnostic Challenges in Thrombotic Microangiopathies

The Alexion Satellite Symposium provided an introduction to thrombotic microangiopathies (TMA) by Prof Dirk Kuypers, who described atypical haemolytic…
18 Jul 2014

Bringing the Benefits of High-Dose Haemodialysis to the Home with a Novel Haemodialysis System

Haemodialysis (HD) is a haemodynamically traumatic practice that is known to cause ischaemic insult to a variety of organs. Reductions in perfusion…
18 Jul 2014

Pain in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder affecting 1 in 1,000 people and is responsible for 10% of cases of…
18 Jul 2014

Autosomal Dominant Polycystic Kidney Disease: Review and Management Update

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal…