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Therapy Area
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Flagship Journal
Gastroenterology
General Healthcare
Hematology
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SGLT2 Computational Structural Studies Investigating Polypharmacy
1
Mins
July 2024
Widespread use of SLGT2 inhibitors (SGLT2i) is likely given recent recommendations for their use in chronic kidney disease and heart…
Read more
1
Mins
30 Jul 2019
Allo-Haemodialysis as a Novel Renal Replacement Modality: Urea Kinetics in a Paediatric Use Case
Lack of affordable renal replacement therapy (RRT), especially in limited resource settings, puts patients with kidney failure at the risk of imminent…
2
Mins
30 Jul 2019
Kt/V Achievement and Mortality in Haemodialysis Patients in the Gulf Cooperation Council (GCC) Countries: Results from DOPPS (2012-2018)
Adequate dialysis, as measured by Kt/V, is important for maintaining good health in haemodialysis (HD) patients. Guidelines recommend single pool Kt/V…
2
Mins
30 Jul 2019
Changes in Intraocular Pressure During Haemodialysis and the Role of Ultrafiltration Rate
Ocular problems have been reported to exist in patients with end-stage renal disease (ESRD). Discounting ageing itself, which is a known risk factor…
1
Mins
30 Jul 2019
Changes of Salivary Creatinine and Urea in Animal Models of Kidney Disease
Plasma creatinine and urea are widely used as markers of renal function. Saliva is an alternative diagnostic fluid with many advantages in comparison…
2
Mins
30 Jul 2019
Impact of Chronic Kidney Disease on the Drugs Eliminated Predominantly Through a Non-Renal Route: A Proof of Concept Study with Citalopram
Drug dosing in patients with chronic kidney disease (CKD) can be challenging due to the exclusion of such patients in the clinical trials during the drug…
1
Mins
30 Jul 2019
A Novel Mechanism of Diclofenac’s Action: Inhibition of Kynurenic Acid Production in Rat Kidney In Vitro
Non-steroidal anti-inflammatory drugs (NSAID) are one of the most popular analgesics due to their efficacy and availability over the counter.1 However…
1
Mins
12 Jul 2018
Higher Phthalate Exposure May Increase Urothelial Cancer Risk in Patients with Chronic Kidney Disease
Phthalates can disturb the endocrine system and are reported to have associations with breast cancer. Patients with chronic kidney disease (CKD) are…
1
Mins
12 Jul 2018
Aiming to Increase Adherence to Treatment in Patients with Chronic Kidney Disease: The Use of Technology
Chronic kidney disease (CKD) is a public health problem worldwide, and, in Brazil, an increasing number of patients requiring dialysis and…
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