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5 Nov 2019

Trends in the Incidence of Prediabetes Among Younger and Older Immigrants in Canada, 2011–2017

The burden of prediabetes appears to be increasing worldwide. According to the International Diabetes Federation (IDF), low and middle-income countries…
2 Mins
5 Nov 2019

Once-Weekly Semaglutide versus Daily Canagliflozin in Type 2 Diabetes Mellitus (SUSTAIN 8): How Do They Compare?

Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium–glucose cotransporter-2 inhibitors (SGLT-2i) are effective and well-tolerated…
2 Mins
5 Nov 2019

SUSTAIN 10: Efficacy and Safety of Semaglutide 1.0 mg Once Weekly versus Liraglutide 1.2 mg Once Daily

Subcutaneous semaglutide once weekly (OW) and subcutaneous liraglutide once daily (OD) are two glucagon-like peptide-1 receptor agonists (GLP-1RA)…
2 Mins
5 Nov 2019

Deep Serum Proteomics Reveal Biomarkers and Causal Candidates for Type 2 Diabetes Mellitus

The prevalence of Type 2 diabetes mellitus  (T2DM) is expected to increase rapidly in the next decades, posing a major challenge to societies worldwide.
2 Mins
5 Nov 2019

Effect of the Time of Day of Food Intake and Eating Occasions on Clock Gene mRNA Expression, Weight Loss, HbA1c, and Overall Glycaemia in Type 2 Diabetes Mellitus

Most of the metabolic processes involved in obesity, glycaemic control (i.e., β-cell function), muscular glucose uptake, and hepatic glucose production…
2 Mins
20 Nov 2018

Implementation of an Aggressive Management of Insulin Therapy and Carbohydrates Intake During a Trail-Running Endurance Competition in Athletes with Type 1 Diabetes Mellitus

The idea to test the implementation of an aggressive insulin and carbohydrate intervention strategy approach to Type 1 diabetes mellitus (T1DM) athletes…
2 Mins
20 Nov 2018

Abdominal Subcutaneous Adipose Tissue Gene Expression in Relation to Tissue-Specific Insulin Resistance in Human Obesity

Obesity and being overweight are major risk factors for several diseases, including cardiovascular disease and Type 2 diabetes mellitus. Adipose tissue…
2 Mins
20 Nov 2018

Variants in Genes (DHCR7, CYP2R1, and GC) Regulating Vitamin D Metabolism Determine Low Vitamin D Levels in Type 2 Diabetic Patients

Hypovitaminosis D is associated with an increased prevalence and incidence of metabolic syndrome and Type 2 diabetes mellitus (T2DM).