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18 Jul 2019

“I Look Disgusting”: A Qualitative Enquiry into the Impact of Atopic Dermatitis on Quality of Life in Adults

Atopic dermatitis (AD) has been related to poorer health-related quality of life (HRQoL) in adults, but no qualitative research has been published…
2 Mins
18 Jul 2019

Hereditary Alpha-Tryptasaemia Due to TPSAB1 Gene Duplication is Associated with Multifocal Sclerotic Bone Disease

Hereditary alpha-tryptasaemia (HAT) affects 4–6% of the population and is caused by allelic replications tandem duplications of the alpha-tryptase encoding…
2 Mins
18 Jul 2019

IgE Signalling Repression by a Designer DNA Vaccine to Modulate Shrimp Hypersensitivity

Shellfish is one of the most common food allergens worldwide, causing frequent anaphylaxis in both paediatric and adult populations. Despite the…
1 Mins
17 Jul 2018

Epigenetic Dysregulation of Naïve CD4+ T Cell Activation Genes in Childhood Food Allergy

Food allergy poses a significant clinical and public health burden, affecting 2–10% of infants, and T cell dysfunction has been previously reported in…
2 Mins
17 Jul 2018

Evaluation of a Treatment Scheme with the Recombinant Grass Pollen Allergy Vaccine BM32: Yielding High Allergen-Specific Immunoglobulin G Responses Associated with Clinical Efficacy

This European Academy of Allergy and Clinical Immunology (EAACI) presentation discussed the clinical development programme of a new B cell epitope-based…
2 Mins
17 Jul 2018

Microcrystalline Tyrosine: An Appropriate Alternative to Aluminium as Adjuvant in Vaccines and Allergen Immunotherapy

Adjuvants are compounds added to antigens in vaccines to increase the body’s immune response to an antigen.1 Similarly, adjuvants are added to allergens…
1 Mins
17 Jul 2018

Allergy Prevention by Allergens Depends on Their Ligands

The prevalence of allergy in the Western world is increasing, with 35% of women and 24% of men in Germany affected.1 It is unclear why atopic individuals…
1 Mins
17 Jul 2018

Response to Omalizumab in Urticaria and Asthma: Is it a ‘Lifetime Together’ Treatment?

Omalizumab is a recombinant human monoclonal antibody that blocks the immunoglobulin (Ig)E receptor and is indicated in cases of severe asthma (SA)…