A NEW study has revealed a significant decline in lung cancer deaths among individuals with chronic lower respiratory diseases (CLRD) in the United States over the past two decades. However, certain demographic and regional groups continue to face disproportionately high mortality rates.
The study analysed data from the CDC WONDER database spanning 1999–2020. Researchers calculated age-adjusted mortality rates (AAMR) for lung cancer deaths among CLRD patients and examined trends across demographic, geographic, and temporal groups.
The findings show that while CLRD-associated lung cancer deaths decreased from 21.6 per 100,000 in 1999–2004 to 17.2 per 100,000 in 2016–2020, disparities remain stark. Mortality rates were highest among White Americans, men (AAMR = 25.05), and adults aged 65 and older (AAMR = 44.78). Geographically, the Midwest and South showed higher rates compared to the Northeast, with rural areas experiencing the greatest burden (AAMR ratio = 1.44).
“While overall progress is encouraging, these disparities highlight an ongoing need to address risk factors and healthcare access among vulnerable populations,” the authors noted.
The study underscores the importance of targeted interventions and resources to support older adults, rural communities, and specific demographic groups disproportionately affected by CLRD-associated lung cancer deaths. Continued efforts are essential to reduce these inequities and improve outcomes nationwide.
Aleksandra Zurowska, EMJ
Reference
Grobman B et al. Disparities in Lung Cancer Death Among People with Chronic Lower Respiratory Diseases in the United States. Lung. 2025;DOI: 10.1007/s00408-024-00756-5.
