The causes and consequences of tumour evolution and heterogeneity - European Medical Journal

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The causes and consequences of tumour evolution and heterogeneity

Oncology
At the European Cancer Congress (ECC) 2015, Charles Swanton, FRCP, BSc, PhD, of The Francis Crick Institute and Cancer Research UK London Research Institute, London, UK, reviews the emerging understanding of mutational drivers of tumour heterogeneity, including APOBEC-mediated mutagenesis, that could support the development of future therapeutic strategies.

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