Neoadjuvant abiraterone acetate plus leuprolide acetate in localised high-risk prostate cancer - European Medical Journal

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Neoadjuvant abiraterone acetate plus leuprolide acetate in localised high-risk prostate cancer

Oncology
At the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, Eleni Efstathiou, MD, PhD, of The University of Texas MD Anderson Cancer Center, Houston, TX, discusses a study that evaluated the clinical and biological heterogeneity of response and resistance to neoadjuvant abiraterone acetate, a prodrug of abiraterone, a CYP17 inhibitor that lowers serum testosterone, plus leuprolide acetate, a luteinizing hormone-releasing hormone agonist (LHRHa), versus LHRHa for patients with localised high-risk prostate cancer.

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