A pioneering breast cancer initiative, the Personalised Breast Cancer Programme (PBCP), is set to expand to Norfolk and Norwich University Hospital, providing more patients in the East with access to advanced, tailored treatment. Initially launched at Addenbrooke’s Hospital, the program now extends to its fourth site in the region, following successful rollouts in Ipswich, Colchester, and Oxford.
The PBCP utilizes whole genome sequencing, allowing healthcare providers to decode the genetic makeup of a patient’s cancer. This innovative approach enables personalized treatment plans based on individual genetic profiles, with results typically available within six to twelve weeks. Since its inception, over 1,500 patients have participated, with many seeing changes in their treatment protocols based on genetic insights.
Professor Jean Abraham, who leads the program, emphasised the importance of understanding each patient’s unique genetic mutations. “This information helps direct clinicians to the most effective treatments, including potential participation in clinical trials,” she explained. The program is particularly crucial for patients with hypermutated tumours, which may respond better to immunotherapy.
As Breast Cancer Awareness Month unfolds, the PBCP’s expansion marks a significant milestone in improving cancer care across the East of England, aiming to boost survival rates and enhance patient outcomes.
Helena Bradbury, EMJ
Reference
More patients in the East to benefit from personalised breast cancer treatment. Available at: https://www.cuh.nhs.uk/news/more-patients-in-the-east-to-benefit-from-personalised-breast-cancer-treatment/. Last accessed: 23 October 2024.
