Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review - European Medical Journal

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Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review

Nephrology
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Authors:
*Cosimo Marcello Bruno,1 Gabriele Pricoco,1 Damiano Cantone,1 Elisa Marino,1 Francesca Bruno2

1. Department of Clinical and Experimental Medicine, Section of Internal and Emergency Medicine, University of Catania, Catania, Italy
2. Department of Clinical and Experimental Medicine, Section of Nephrology, University of Catania, Catania, Italy
*Correspondence to [email protected]

Disclosure:

The authors have declared no conflicts of interest.

Received:
11.03.16
Accepted:
26.05.16
Citation:
EMJ Nephrol. ;4[1]:92-97. DOI/10.33590/emjnephrol/10311174. https://doi.org/10.33590/emjnephrol/10311174.
Keywords:
Uric acid, urate transport, tubular handling, urate clearance

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Abstract

In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and insulin-resistance on renal clearance of uric acid.

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