A RECENT systematic review and meta-analysis has identified several effective and cost-efficient strategies to enhance measles vaccination coverage and timeliness in low-income and middle-income countries (LMICs). The study evaluated various interventions aimed at increasing measles immunization rates among children under 5.
Researchers conducted a comprehensive search of English-language articles from 2012 to July 2023 across eight databases, including PubMed, ProQuest, and MEDLINE. Out of 44 identified articles, 14 met the criteria for inclusion in the meta-analysis. The analysis revealed that targeted interventions, such as vaccination reminders, cash incentives, community engagement, and health education activities, significantly increased measles vaccination coverage, with a relative risk (RR) of 1.19 (95% CI 1.10 to 1.27).
In addition to improving overall coverage, these strategies also enhanced the timeliness of vaccinations. Interventions like vaccine reminders, educational programs, and financial incentives were particularly effective in ensuring children received vaccinations at the recommended ages.
The study also assessed the cost-effectiveness of various approaches. Strategies such as geographically informed microplanning, unrestricted vial opening, supplementary immunization activities, community engagement, outreach programs, and financial incentives were identified as both effective and economical. Tailoring these interventions to local contexts is crucial for maximizing their impact and protecting children from measles and its associated complications.
For healthcare professionals and policymakers, these findings underscore the importance of implementing multifaceted and context-specific strategies to improve measles vaccination rates in LMICs. By adopting these evidence-based approaches, it is possible to enhance immunization coverage, ensure timely vaccinations, and ultimately reduce measles-related morbidity and mortality.
Reference: Yitbarek K et al. Impact of measles vaccination strategies on vaccination rates in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Glob Health. 2025;10(2):e016647.
Anaya Malik | AMJ
