Hema Now: Episode 11: Decoding Leukaemia's Epigenetic Drivers - European Medical Journal

Hema Now: Episode 11: Decoding Leukaemia’s Epigenetic Drivers

Hematology

Hema Now | Episode 11

This week, Jonathan is joined by Eytan Stein, Chief of the Leukaemia Service and an Attending Physician at Memorial Sloan Kettering Cancer Center, New York, USA.

Spotify | Apple | Amazon Music | YouTube | Download MP3 (24 mins)

Speaker bio: 

Eytan Stein

Eytan Stein

Eytan Stein is the Chief of the Leukemia Service and an Attending Physician at Memorial Sloan Kettering Cancer Center in New York, USA. His research focuses on acute and chronic leukaemias, myelodysplastic syndromes, and myeloproliferative neoplasms.

Stein’s academic journey began with a bachelor’s degree in political science from the University of Pennsylvania, followed by earning his medical degree from Northwestern University in Chicago. He completed his post-doctoral training at several esteemed institutions, including Northwestern Memorial Hospital, Weill Cornell Medical College, and Memorial Sloan Kettering Cancer Center.

Timestamps:
00:00 – Introduction
01:05 – The current landscape of treatments
02:26 – The promise and peril of differentiation therapy
05:55 – Highlighting the most impactful clinical trials
08:38 – Epigenetics and the future of targeted therapies
10:40 – The BEAT AML master clinical trial
12:57 – The latest research into IDH inhibitors
16:10 – Therapies for splicing factor mutations
19:29 – Reducing patient fear with education
22:46 – Stein’s three wishes for healthcare

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