Immune-mediated inflammatory diseases, including rheumatoid arthritis, axial spondyloarthritis, psoriasis, hidradenitis suppurativa, and inflammatory bowel disease, affect up to 10% of the Western population. Due to their overlapping pathogeneses, these chronic inflammatory diseases are now treated according to their pathological mechanism. These mechanisms involve the increased production of the cytokine tumour necrosis factor (TNF)-α, leading to excessive inflammation and consequently to organ damage.
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7 Mins
13th
March
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Altered gut microbiome profiles correlate with anxiety and depression in humans, and work in animal models has identified specific…
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5 Mins
13th
March
Systemic Health Impact of Leaky Barriers in the Oral-Gut-Brain Axis
The human body is a holistic system, interconnected by the circulatory, nervous, lymphatic, endocrine, and immune systems that facilitate…
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5 Mins
13th
March
Intersection of the Upper Gastrointestinal Microbiome and Oesophageal Cancer
The upper gastrointestinal microbiome, a complex ecosystem of microorganisms that have historically been difficult to identify, may play a…
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6 Mins
19th
December
Interview: Jonathan A. Leighton
Capsule endoscopy was truly a disruptive technology that I had the opportunity to get involved with early on. Disruptive technologies do not come along very often…
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