Uncategorised - European Medical Journal

The Importance of the mTOR Regulatory Network in Chondrocyte Biology and Osteoarthritis

Osteoarthritis (OA) is a chronic disorder associated mainly with pain, limited range of motion, stiffness, joint inflammation, and articular cartilage…

Why Basic Calcium Phosphate Crystals Should Be Targeted In the Treatment of Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and results in significant social, psychological, and economic costs. It is characterised by…

Extra-Articular Manifestations of Rheumatoid Arthritis, Now

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease, characterised by polyarthritis and extra-articular organ disease, including…

Antiphospholipid Syndrome Novel Therapies

Antiphospholipid syndrome (APS) is an autoimmune disease characterised by arterial and/or venous thrombosis, recurrent pregnancy loss, and persistently…

Diagnostic Challenges in Thrombotic Microangiopathies

The Alexion Satellite Symposium provided an introduction to thrombotic microangiopathies (TMA) by Prof Dirk Kuypers, who described atypical haemolytic…

Bringing the Benefits of High-Dose Haemodialysis to the Home with a Novel Haemodialysis System

Haemodialysis (HD) is a haemodynamically traumatic practice that is known to cause ischaemic insult to a variety of organs. Reductions in perfusion…

Pain in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder affecting 1 in 1,000 people and is responsible for 10% of cases of…

Autosomal Dominant Polycystic Kidney Disease: Review and Management Update

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited nephropathy. Initially, it is characterised by the growth of renal…

Chronic Kidney Disease – Where Next? Predicting Outcomes and Planning Care Pathways

With the introduction of the National Kidney Foundation Kidney Disease Outcomes Quality Initiative chronic kidney disease (CKD) guidelines, CKD has been…

No Added Mortality Benefit From Current Approaches to Renal Replacement Therapy in ICU Patients

Hospital-acquired acute kidney injury (AKI), a common and harmful renal disorder, is an independent risk factor for short-term and long-term mortality…