Uncategorised - European Medical Journal

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Pharma to FDA: upgrade cell and gene data sharing

The pharmaceutical industry is calling on the FDA to modernise how it tracks the long-term safety and efficacy of cell and gene therapies.

Why Rheumatoid Arthritis Remission Rates Remain Stagnant

A national cohort study shows rheumatoid arthritis remission rates in England and Wales have plateaued since 2018, with wide regional variation and delays before specialist referral limiting progress

Obesity -Related MASLD Risk Stratification Urged in New Liver Study

New research calls for routine risk stratification of MASLD in people with obesity to detect and manage liver disease earlier.

Cyclophosphamide Adds No Benefit in Low-Risk EGPA

A target trial emulation study finds no relapse reduction with cyclophosphamide added to glucocorticoids in eosinophilic granulomatosis with polyangiitis without poor-prognosis factors.

Robot-Based Therapy for Autism Shows Promise

Find out how robot-assisted therapy for autism matches standard treatment outcomes while improving engagement and expanding access in clinical and community settings.

Chemotherapy Linked to Impaired Ovarian Function in New Research

A recent study links chemotherapy to impaired ovarian function and fertility through oxidative damage to ovarian follicles.

Iron Infusion Raises Haemoglobin Before Delivery

Randomised trial shows intravenous iron significantly improves maternal haemoglobin before delivery in non-anaemic iron deficient pregnancy, supporting ferritin screening and targeted treatment in antenatal care.

Novel Antibiotic Provides Symptom Relief in Uncomplicated UTI

Pooled trial data show gepotidacin provides early, meaningful symptom relief comparable to nitrofurantoin in uncomplicated urinary tract infection.

Blood Inflammation Ratio Tied to Diabetic Nephropathy

Meta-analysis shows neutrophil to lymphocyte ratio is associated with higher risk and progression of diabetic nephropathy, supporting its potential use as an inflammatory biomarker in clinical practice.

Biologic Persistence Varies by Prior Exposure in Psoriasis Treatment

Real-world Danish registry data show that biologic drug survival in psoriasis differs between biologic-naive and bioexperienced patients.