Uncategorised - European Medical Journal

Efficacy and Safety of Upadacitinib in SELECT-GCA Phase III Trial Results: ACR24

A Phase III clinical trial presented at ACR Convergence 2024 revealed that upadacitinib (UPA), combined with a 26-week glucocorticoid (GC) improved disease control and reduced steroid exposure compared to a placebo (PBO) regimen in patients with giant cell arteritis (GCA).

Global Recruiting Patterns Linked To Placebo Responses in PsA Clinical Trials: ACR24

Presented at the ACR Convergence 2024, new research highlighted how changing global recruitment patterns influence placebo response rates in clinical trials for psoriatic arthritis (PsA).

Breakthrough Neuron-Wrapping Devices Could Transform Neurological Treatments

A new wireless device that wraps around neurons may transform treatment for neurological disorders, aiding neuron function by acting as synthetic myelin.

Percutaneous Aspiration Offers Hope for Patients with Right-Sided Infective Endocarditis

The CLEAR-IE study highlights the clinical effectiveness of percutaneous mechanical aspiration in treating right-sided infective endocarditis resistant to medical therapy.

Blood Flow Restriction Therapy Boosts Knee Osteoarthritis Recovery

Blood flow restriction therapy shows greater pain and strength improvements in knee osteoarthritis, study finds.

Cardiovascular Disease in Pregnancy Tied to Higher Mortality Rates

Pregnant patients with cardiovascular disease face a significantly increased risk of severe maternal morbidity and mortality, according to a large US-based study.

New Approach Offers Hope for Drug-Resistant Lung Cancer

Researchers have developed a novel treatment for non-small cell lung cancer (NSCLC) that uses customised antisense oligonucleotides (ASOs) to selectively target drug-resistant EGFR mutations.

Early RSV Vaccination in Pregnancy Enhances Neonatal Protection

he study aimed to evaluate how gestational age at the time of vaccination and the time elapsed until delivery impacted antibody levels in the newborn.

Roux-en-Y: Sustained Weight Loss and Diabetes Remission 15 Years On

A retrospective study analysed over 15 years of follow-up data from patients who underwent Roux-en-Y gastric bypass.

Local Dengue Cases Drive Rapid Public Health Measures

In October 2023, a confirmed local dengue case in Pasadena, California marked a concerning milestone for the state’s public health officials.