Ethics of Treating Actinic Keratosis in Patients of Advanced Age - European Medical Journal

Ethics of Treating Actinic Keratosis in Patients of Advanced Age

1 Mins
Dermatology
Download PDF
Authors:
* Samer Wahood , 1 Shivani Jain , 2 Megan Hoang , 1 Idowu Olugbade , 1 Nicole A. Negbenebor 3
  • 1. The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
  • 2. Louisiana State University Health Sciences Center-New Orleans School of Medicine, USA
  • 3. Dermatology and Director of Skin of Color Clinic, Department of Dermatology, University of Iowa, Iowa City, USA
*Correspondence to [email protected]
Disclosure:

The authors have declared no conflicts of interest.

Citation:
Keywords:
Actinic keratosis (AK), cryotherapy, geriatrics, medical ethics, premalignant lesion, quality of life.

Each article is made available under the terms of the Creative Commons Attribution-Non Commercial 4.0 License.

INTRODUCTION

This ethics discussion highlights the complexities of treating actinic keratoses (AK) in elderly patients, particularly those in their ninth decade of life or beyond.1 AKs are recognized as precursors to squamous cell carcinoma,2 and timely interventions can reduce the likelihood of progression to invasive disease.3,4

ETHICAL ANALYSIS

Clinicians must carefully balance the principles of beneficence and nonmaleficence, as treatments such as cryotherapy and topical therapies (e.g., 5-fluorouracil with calcipotriol) may cause discomfort, scarring, or dyspigmentation.2 These adverse effects can be especially concerning in older patients whose overall quality of life and comfort may be prioritized over aggressive treatment.

Financial factors also weigh into decision-making. Although cryotherapy is relatively quick and frequently reimbursed,5 it may pose an economic burden on patients and their caregivers. The principle of justice requires that medical resources be allocated wisely, taking into account both the cost to the healthcare system and the patient’s out-of-pocket expenses. Clinicians should remain mindful of whether frequent, potentially painful procedures for minor lesions offer a net benefit for a frail patient with multiple comorbidities.

Finally, respecting patient autonomy is essential. Involving the patient when capacity is intact and any caregivers in discussing goals of care helps clarify the most ethically appropriate management strategy. For some individuals, cosmetically unimportant or minimally symptomatic AKs may not warrant aggressive treatment, particularly if other medical issues take precedence.

CONCLUSION

Ultimately, ethical AK management in advanced age requires a patient-centered approach that integrates clinical judgment, compassionate care, and open communication.

References
Wahood S et al. Ethics of treating actinic keratoses in patients of advanced age. Abstract 64667. American Academy of Dermatology Annual Meeting, March 7-11, 2025. Worley B et al. Treatment of actinic keratosis: a systematic review. Archives of Dermatological Research. 2023 Jul;315(5):1099-108. Green AC, Olsen CM. Cutaneous squamous cell carcinoma: an epidemiological review. Br J Dermatol. 2017;177(2):373-81. Dika E et al. Pain evaluation in patients affected by cutaneous squamous cell carcinoma and actinic keratosis: an observational study. G Ital Dermatol Venereol. 2016;152(5):413-7. Yeung H et al. Use and cost of actinic keratosis destruction in the Medicare Part B fee-for-service population, 2007 to 2015. JAMA dermatology. 2018;154(11):1281-5.

Rate this content's potential impact on patient outcomes

Average rating / 5. Vote count:

No votes so far! Be the first to rate this content.