European Archives - Page 822 of 989 - European Medical Journal

Unsupervised Transcriptomics-Based Clustering of Ulcerative Colitis Patients Reveals Marked Heterogeneity that Relates to Anti-Tumour Necrosis Factor Treatment Response

Heterogeneity within inflammatory bowel disease cohorts is often cited as the biggest challenge to reliably studying the clinical efficacy of therapeutics.

Barrett’s Oesophagus in 2016

Barrett’s oesophagus (BO) is one of the most important complications of gastro-oesophageal reflux disease as it may progress to oesophageal adenocarcinoma.

Monoclonal Antibody-Based Therapy for Eosinophilic Oesophagitis

Eosinophilic oesophagitis is an inflammatory condition associated with marked eosinophil accumulation in the mucosal tissues of the oesophagus.

Addition of a Solid Test Meal to Oesophageal High Resolution Manometry Improves Diagnostic Yield And Identifies Dysmotility as the Cause of Patient Symptoms

The use of oesophageal high resolution manometry (HRM) to evaluate patients who present with oesophageal symptoms in the absence of a structural lesion…

Orchard Therapeutics Announces Strategic Alliance with Oxford BioMedica

United Kingdom, November 29, 2016 – Orchard Therapeutics (“Orchard”), a biotechnology company dedicated to bringing transformative ex-vivo gene therapies…

Janssen Submits Application to EMA Seeking Approval of Anti-Interleukin-23 Monoclonal Antibody Guselkumab for the Treatment of Moderate to Severe Plaque Psoriasis

Janssen announced today the submission of a Marketing Authorisation Application to the EMA seeking approval of guselkumab for the treatment of adults living with moderate to severe plaque psoriasis.

Astronauts’ Visual Impairment Involves Changes in Cerebrospinal Fluid

OCULAR impairments experienced by astronauts are linked to space-induced volume changes in cerebrospinal fluid (CSF), according to research presented…

Personalised Risk Estimates of Diabetes Does Not Motivate Healthy Behaviour

COMMUNICATING personalised information about genetic and phenotypic risks of Type 2 diabetes does not motivate positive behaviour change in the…

Promising Inhibitory Human Monoclonal Antibody Discovery in The Fight Against Zika

ZIKA virus infection of expectant mothers can have devastating consequences, particularly for the fetus, and yet at present no vaccine is available. At…

EMJ

Newborn Telomere Length Shortened by Maternal Obesity

FETAL PROGRAMMING and epigenetic influences are current topics of extensive debate. Although the impacts of smoking and alcohol consumption during…