European Archives - Page 776 of 995 - European Medical Journal

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9 Mins
8 Aug 2017

Patients in Focus: What’s Relevant for Chronic Myeloid Leukaemia and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia?

This symposium was dedicated to discussing BCR-ABL-positive chronic myeloid leukaemia (CML) and Philadelphia-positive acute lymphoblastic leukaemia (Ph+ALL)
8 Mins
8 Aug 2017

Editor’s Pick: The Role and Regulation of Quiescence in Acute Lymphoblastic Leukaemia

There are ˜3,000 children, as well an additional ˜7,000 adults, diagnosed with acute lymphoblastic leukaemia (ALL) each year in the USA.
1 Mins
8 Aug 2017

Oral Rigosertib Combined With Azacitidine in Patients with Myelodysplastic Syndromes and Acute Myeloid Leukaemia: Effects in Treatment Naïve and Relapsed/ Refractory Patients

Azacitidine is the standard of care for higher risk myelodysplastic syndromes (MDS); however, only approximately 50% of patients respond, and those…
7 Mins
8 Aug 2017

Thrombocytopenia: A Defect in Actin Dynamics?

The actin cytoskeleton plays many important roles in the lifecycle of platelets, from biogenesis from megakaryocytes, to activation and clearance from…
2 Mins
8 Aug 2017

Minimal Residual Disease Monitoring by Digital PCR for JAK2V617F Detection in Patients with Myelofibrosis or Acute Myeloid Leukaemia Secondary to Myelofibrosis after Allogeneic Stem Cell Transplantation

Myelofibrosis (MF) is one of the BCR-ABL1-negative chronic myeloproliferative neoplasms (MPNs), characterised by clonal expansion of abnormal…
8 Mins
8 Aug 2017

The Role of Allograft in Acute Lymphoblastic Leukaemia, Including Alternate Donors

The management of acute lymphoblastic leukaemia (ALL) remains challenging.
12 Mins
8 Aug 2017

Double-Hit and Triple-Hit Lymphomas: New Perspectives for Their Classification

In 2016, an update on the classification of lymphoid neoplasm was published, and one of the modifications made focussed on B-cell lymphoma…
9 Mins
8 Aug 2017

Management of Adult Patients with Myelodysplastic Syndromes

The myelodysplastic syndromes form a heterogeneous group of clonal disorders with an increasing incidence in the elderly population and an emerging…
7 Mins
8 Aug 2017

Different Therapeutic Interventions and Mechanisms of Action of Antisickling Agents Currently in Use in Sickle Cell Disease Management

Sickle cell disease is a genetic disorder caused by sickle haemoglobin. In many forms of the disease, the red blood cells can change shape upon…
7 Aug 2017

Networking with Neurology Attending Congress: A First Timer’s Perspective

If you had asked me what the word congress meant to me a year ago, the connotations would have been extremely different to those which I picture today.